Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FIGNFidgetin, microtubule severing factor. (639 aa)    
Predicted Functional Partners:
IST1
IST1 factor associated with ESCRT-III.
    
 0.968
UBXN7
UBX domain protein 7.
   
 0.916
ENSSARP00000000627
annotation not available
   
 0.896
ENSSARP00000006823
annotation not available
   
 0.869
SPIDR
Scaffold protein involved in DNA repair.
    
 0.830
RAD51
RAD51 recombinase.
  
 0.812
ENSSARP00000004167
annotation not available
    
 
 0.758
ENSSARP00000001551
annotation not available
   
 0.739
ENSSARP00000001205
annotation not available
    
 0.734
WRN
WRN RecQ like helicase.
   
 0.731
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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