Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000001575annotation not available (188 aa)    
Predicted Functional Partners:
SMC5
Structural maintenance of chromosomes 5.
   
 0.992
ENSSARP00000011914
annotation not available
   
 0.991
NSMCE2
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.990
SMC6
Structural maintenance of chromosomes 6.
   
 0.990
SLF1
SMC5-SMC6 complex localization factor 1.
    
 0.849
RANBP2
RAN binding protein 2.
   
 0.805
STN1
STN1 subunit of CST complex.
    
   0.790
TP53
Tumor protein p53.
    
 0.788
NPAS4
Neuronal PAS domain protein 4.
    
 0.745
ENSSARP00000008146
annotation not available
   
 0.723
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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