STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDGFRAPlatelet derived growth factor receptor alpha. (1090 aa)    
Predicted Functional Partners:
PDGFB
Platelet derived growth factor subunit B.
   
 0.999
PDGFC
Platelet derived growth factor C.
    
 0.986
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.969
PDGFD
Platelet derived growth factor D.
    
 0.964
ENSSARP00000008071
annotation not available
   
 0.958
EGFR
Epidermal growth factor receptor.
   
0.953
FGF7
Fibroblast growth factor 7.
   
 0.945
FGF20
Fibroblast growth factor 20.
   
 0.944
ENSSARP00000011431
annotation not available
   
 0.944
FGF21
Fibroblast growth factor 21.
    
 0.942
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.