Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DIRAS2DIRAS family GTPase 2. (199 aa)    
Predicted Functional Partners:
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.946
RAPGEF4
Rap guanine nucleotide exchange factor 4.
   
 0.912
LRRC17
Leucine rich repeat containing 17.
    
 0.904
ENSSARP00000005431
annotation not available
      
 0.879
RNF19B
Ring finger protein 19B.
    
   0.798
WDR82
WD repeat domain 82.
     
 0.786
EIF2B2
Eukaryotic translation initiation factor 2B subunit beta.
    
 0.781
ENSSARP00000002385
annotation not available
    
 0.747
RAPGEF2
Rap guanine nucleotide exchange factor 2.
    
 0.747
ENSSARP00000009965
annotation not available
    
 
 0.741
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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