Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHL28Kelch like family member 28. (571 aa)    
Predicted Functional Partners:
KLHL14
Kelch like family member 14.
    
  0.953
IPP
Intracisternal A particle-promoted polypeptide.
    
  0.943
KLHL24
Kelch like family member 24.
   
   0.921
ENSSARP00000007950
annotation not available
    
 0.921
CUL3
Cullin 3.
    
 0.921
KLHL26
Kelch like family member 26.
    
  0.901
NUDCD3
NudC domain containing 3.
    
 
 0.874
KEAP1
Kelch like ECH associated protein 1.
    
   0.812
ENSSARP00000006941
annotation not available
    
  0.689
ENSSARP00000010357
annotation not available
    
  0.689
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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