Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (838 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes 3.
   
 0.981
PDS5A
PDS5 cohesin associated factor A.
    
 0.964
ENSSARP00000003677
annotation not available
   
 0.953
CHTF18
Chromosome transmission fidelity factor 18.
   
 
 0.944
PDS5B
PDS5 cohesin associated factor B.
   
 0.939
ENSSARP00000008146
annotation not available
   
 0.930
RAD21
RAD21 cohesin complex component.
   
 0.930
ATAD5
ATPase family AAA domain containing 5.
   
 0.910
ESCO2
Establishment of sister chromatid cohesion N-acetyltransferase 2.
  
  
0.907
ENSSARP00000012213
annotation not available
   
 
 0.894
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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