Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LDLRAD4Low density lipoprotein receptor class A domain containing 4. (305 aa)    
Predicted Functional Partners:
SMAD2
SMAD family member 2.
    
 0.984
ENSSARP00000008126
annotation not available
    
 
 0.937
SMURF1
SMAD specific E3 ubiquitin protein ligase 1.
    
   0.877
ENSSARP00000004038
annotation not available
    
 
 0.867
FBL
Fibrillarin.
   
 
 0.834
ENSSARP00000000040
annotation not available
    
 
 0.815
PRMT5
Protein arginine methyltransferase 5.
   
 0.814
SMURF2
SMAD specific E3 ubiquitin protein ligase 2.
    
 
 0.794
ERH
ERH mRNA splicing and mitosis factor.
   
  0.785
TMEM161A
Transmembrane protein 161A.
      
 0.775
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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