STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOPBP1DNA topoisomerase II binding protein 1. (1475 aa)    
Predicted Functional Partners:
CDC45
Cell division cycle 45.
   
 0.998
ATRIP
ATR interacting protein.
    
 0.996
BRCA1
BRCA1 DNA repair associated.
   
 0.996
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.996
ENSSARP00000011203
annotation not available
   
 0.993
TP53BP1
Tumor protein p53 binding protein 1.
    
 
 0.991
ENSSARP00000003872
annotation not available
   
 0.989
MCM3
Minichromosome maintenance complex component 3.
   
 0.987
RAD9B
RAD9 checkpoint clamp component B.
    
 0.985
ENSSARP00000002178
annotation not available
    
 0.985
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.