MPP1 protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MPP1

Membrane palmitoylated protein 1. (428 aa)

Predicted Functional Partners:

APBA1

0.958

ENSSARP00000003725

0.946

LIN7C

0.944

LIN7B

0.944

ENSSARP00000005866

0.861

EPS8

0.848

EPB41

0.839

SDC2

0.822

ENSSARP00000001162

0.803

ENSSARP00000001861

0.787

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	ENSSARP00000001861	ENSSARP00000010432	ENSSARP00000001861	Amyloid beta precursor protein binding family A member 1.	annotation not available	0.660
APBA1	ENSSARP00000005866	ENSSARP00000010432	ENSSARP00000005866	Amyloid beta precursor protein binding family A member 1.	annotation not available	0.775
APBA1	LIN7B	ENSSARP00000010432	ENSSARP00000010645	Amyloid beta precursor protein binding family A member 1.	Lin-7 homolog B, crumbs cell polarity complex component.	0.964
APBA1	LIN7C	ENSSARP00000010432	ENSSARP00000001741	Amyloid beta precursor protein binding family A member 1.	Lin-7 homolog C, crumbs cell polarity complex component.	0.964
APBA1	MPP1	ENSSARP00000010432	ENSSARP00000001711	Amyloid beta precursor protein binding family A member 1.	Membrane palmitoylated protein 1.	0.958
ENSSARP00000001162	ENSSARP00000005866	ENSSARP00000001162	ENSSARP00000005866	annotation not available	annotation not available	0.558
ENSSARP00000001162	MPP1	ENSSARP00000001162	ENSSARP00000001711	annotation not available	Membrane palmitoylated protein 1.	0.803
ENSSARP00000001861	APBA1	ENSSARP00000001861	ENSSARP00000010432	annotation not available	Amyloid beta precursor protein binding family A member 1.	0.660
ENSSARP00000001861	ENSSARP00000003725	ENSSARP00000001861	ENSSARP00000003725	annotation not available	annotation not available	0.449
ENSSARP00000001861	ENSSARP00000005866	ENSSARP00000001861	ENSSARP00000005866	annotation not available	annotation not available	0.595
ENSSARP00000001861	EPB41	ENSSARP00000001861	ENSSARP00000001139	annotation not available	Erythrocyte membrane protein band 4.1.	0.467
ENSSARP00000001861	MPP1	ENSSARP00000001861	ENSSARP00000001711	annotation not available	Membrane palmitoylated protein 1.	0.787
ENSSARP00000003725	ENSSARP00000001861	ENSSARP00000003725	ENSSARP00000001861	annotation not available	annotation not available	0.449
ENSSARP00000003725	ENSSARP00000005866	ENSSARP00000003725	ENSSARP00000005866	annotation not available	annotation not available	0.775
ENSSARP00000003725	LIN7B	ENSSARP00000003725	ENSSARP00000010645	annotation not available	Lin-7 homolog B, crumbs cell polarity complex component.	0.855
ENSSARP00000003725	LIN7C	ENSSARP00000003725	ENSSARP00000001741	annotation not available	Lin-7 homolog C, crumbs cell polarity complex component.	0.855
ENSSARP00000003725	MPP1	ENSSARP00000003725	ENSSARP00000001711	annotation not available	Membrane palmitoylated protein 1.	0.946
ENSSARP00000005866	APBA1	ENSSARP00000005866	ENSSARP00000010432	annotation not available	Amyloid beta precursor protein binding family A member 1.	0.775
ENSSARP00000005866	ENSSARP00000001162	ENSSARP00000005866	ENSSARP00000001162	annotation not available	annotation not available	0.558
ENSSARP00000005866	ENSSARP00000001861	ENSSARP00000005866	ENSSARP00000001861	annotation not available	annotation not available	0.595