Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LTA4HLeukotriene A4 hydrolase. (611 aa)    
Predicted Functional Partners:
ALOX5
Arachidonate 5-lipoxygenase.
    
 0.966
PTGR1
Prostaglandin reductase 1.
     
 0.953
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
    
  0.900
TRIT1
tRNA isopentenyltransferase 1.
    
 0.813
GSR
Glutathione-disulfide reductase.
  
 0.799
ENSSARP00000002244
annotation not available
   
  
 0.732
XPNPEP3
X-prolyl aminopeptidase 3.
  
 
 0.687
ALOX5AP
Arachidonate 5-lipoxygenase activating protein.
      
 0.684
ENSSARP00000003655
annotation not available
  
    0.674
ABCG4
ATP binding cassette subfamily G member 4.
  
 
 0.643
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.