AFP protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AFP

Alpha fetoprotein. (555 aa)

Predicted Functional Partners:

AHSG

0.913

FGA

0.772

PLG

0.766

ENSSARP00000005002

0.766

ENSSARP00000005012

0.766

FGG

0.764

ENSSARP00000000079

0.761

ENSSARP00000008652

0.759

ENSSARP00000002551

0.755

HPX

0.724

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFP	AHSG	ENSSARP00000001733	ENSSARP00000010783	Alpha fetoprotein.	Alpha 2-HS glycoprotein.	0.913
AFP	ENSSARP00000000079	ENSSARP00000001733	ENSSARP00000000079	Alpha fetoprotein.	annotation not available	0.761
AFP	ENSSARP00000002551	ENSSARP00000001733	ENSSARP00000002551	Alpha fetoprotein.	annotation not available	0.755
AFP	ENSSARP00000005002	ENSSARP00000001733	ENSSARP00000005002	Alpha fetoprotein.	annotation not available	0.766
AFP	ENSSARP00000005012	ENSSARP00000001733	ENSSARP00000005012	Alpha fetoprotein.	annotation not available	0.766
AFP	ENSSARP00000008652	ENSSARP00000001733	ENSSARP00000008652	Alpha fetoprotein.	annotation not available	0.759
AFP	FGA	ENSSARP00000001733	ENSSARP00000001970	Alpha fetoprotein.	Fibrinogen alpha chain.	0.772
AFP	FGG	ENSSARP00000001733	ENSSARP00000001991	Alpha fetoprotein.	Fibrinogen gamma chain.	0.764
AFP	HPX	ENSSARP00000001733	ENSSARP00000001005	Alpha fetoprotein.	Hemopexin.	0.724
AFP	PLG	ENSSARP00000001733	ENSSARP00000004987	Alpha fetoprotein.	Plasminogen.	0.766
AHSG	AFP	ENSSARP00000010783	ENSSARP00000001733	Alpha 2-HS glycoprotein.	Alpha fetoprotein.	0.913
AHSG	ENSSARP00000002551	ENSSARP00000010783	ENSSARP00000002551	Alpha 2-HS glycoprotein.	annotation not available	0.895
AHSG	ENSSARP00000005002	ENSSARP00000010783	ENSSARP00000005002	Alpha 2-HS glycoprotein.	annotation not available	0.903
AHSG	ENSSARP00000005012	ENSSARP00000010783	ENSSARP00000005012	Alpha 2-HS glycoprotein.	annotation not available	0.903
AHSG	FGA	ENSSARP00000010783	ENSSARP00000001970	Alpha 2-HS glycoprotein.	Fibrinogen alpha chain.	0.985
AHSG	FGG	ENSSARP00000010783	ENSSARP00000001991	Alpha 2-HS glycoprotein.	Fibrinogen gamma chain.	0.962
AHSG	HPX	ENSSARP00000010783	ENSSARP00000001005	Alpha 2-HS glycoprotein.	Hemopexin.	0.814
AHSG	PLG	ENSSARP00000010783	ENSSARP00000004987	Alpha 2-HS glycoprotein.	Plasminogen.	0.903
ENSSARP00000000079	AFP	ENSSARP00000000079	ENSSARP00000001733	annotation not available	Alpha fetoprotein.	0.761
ENSSARP00000002551	AFP	ENSSARP00000002551	ENSSARP00000001733	annotation not available	Alpha fetoprotein.	0.755