STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTS6-pyruvoyltetrahydropterin synthase. (145 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1.
  
 
 0.993
AKR1B10
Aldo-keto reductase family 1 member B10.
    
  0.901
PRKG2
Protein kinase cGMP-dependent 2.
   
  0.898
PRKG1
Protein kinase cGMP-dependent 1.
   
  0.839
ENSSARP00000000848
annotation not available
     
 0.784
GCHFR
GTP cyclohydrolase I feedback regulator.
     
 0.784
ENSSARP00000011779
annotation not available
    
 
 0.716
PTPN1
Protein tyrosine phosphatase non-receptor type 1.
    
 
 0.676
PTPN4
Protein tyrosine phosphatase non-receptor type 4.
    
 
 0.671
PTPN3
Protein tyrosine phosphatase non-receptor type 3.
    
 
 0.671
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.