STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTS6-pyruvoyltetrahydropterin synthase. (145 aa)    
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1.
  
 
 0.944
PRKG2
Protein kinase cGMP-dependent 2.
    
  0.944
ENSSARP00000001828
annotation not available
    
 0.839
CBR3
Carbonyl reductase 3.
    
 0.839
ENSSARP00000000124
annotation not available
    
 0.829
ENSSARP00000000264
annotation not available
    
 0.829
ENSSARP00000009197
annotation not available
    
 0.794
NUDT15
Nudix hydrolase 15.
    
  0.730
AKR1B10
Aldo-keto reductase family 1 member B10.
    
  0.728
ENSSARP00000000848
annotation not available
     
 0.713
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.