Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKG1Protein kinase cGMP-dependent 1. (686 aa)    
Predicted Functional Partners:
MRVI1
Murine retrovirus integration site 1 homolog.
   
 0.979
PRKG2
Protein kinase cGMP-dependent 2.
     
 
0.949
PPP1R17
Protein phosphatase 1 regulatory subunit 17.
    
 0.949
PLN
Phospholamban.
   
 0.944
PPP1R12A
Protein phosphatase 1 regulatory subunit 12A.
   
 0.942
PLCB1
Phospholipase C beta 1.
    
 0.933
GUCY1A1
Guanylate cyclase 1 soluble subunit alpha 1.
  
 0.931
CREB5
cAMP responsive element binding protein 5.
    
 0.925
ENSSARP00000001543
annotation not available
     
 0.924
ENSSARP00000006884
annotation not available
     
  0.924
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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