Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CBLBCbl proto-oncogene B. (971 aa)    
Predicted Functional Partners:
EGFR
Epidermal growth factor receptor.
    
 0.997
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.997
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
    
 0.995
GRB2
Growth factor receptor bound protein 2.
    
 0.993
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
    
 0.992
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.992
CBL
Cbl proto-oncogene.
  
0.991
LCK
LCK proto-oncogene, Src family tyrosine kinase.
    
 0.988
FYN
FYN proto-oncogene, Src family tyrosine kinase.
    
 0.983
CTNNB1
Catenin beta 1.
   
 0.979
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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