Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000001835annotation not available (1104 aa)    
Predicted Functional Partners:
OCLN
Occludin.
   
 
 0.969
YAP1
Yes associated protein 1.
   
 0.962
TJP1
Tight junction protein 1.
   
 
 0.961
GJA1
Gap junction protein alpha 1.
    
 0.929
ENSSARP00000008612
annotation not available
   
 0.885
CASP3
Caspase 3.
    
 0.846
ENSSARP00000004257
annotation not available
    
 
 0.833
ANLN
Anillin actin binding protein.
    
 0.802
ENSSARP00000011015
annotation not available
    
 0.783
CLDN1
Claudin 1.
   
 
 0.779
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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