Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSPO1R-spondin 1. (228 aa)    
Predicted Functional Partners:
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.994
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.990
ENSSARP00000011521
annotation not available
    
 0.980
ENSSARP00000005463
annotation not available
    
 
 0.878
CHTOP
Chromatin target of PRMT1.
    
   0.836
ENSSARP00000004100
annotation not available
     
  0.819
ENSSARP00000005425
annotation not available
      
 0.798
ENSSARP00000009264
annotation not available
     
 0.748
RCC1
Regulator of chromosome condensation 1.
  
 
 0.740
CTNNB1
Catenin beta 1.
   
 0.726
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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