Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ETS1ETS proto-oncogene 1, transcription factor. (410 aa)    
Predicted Functional Partners:
CREBBP
CREB binding protein.
    
 
 0.949
TP53
Tumor protein p53.
    
 
 0.932
RUNX1
RUNX family transcription factor 1.
   
 0.930
ENSSARP00000006597
annotation not available
   
 0.920
NFKB2
Nuclear factor kappa B subunit 2.
    
 0.912
RUNX2
RUNX family transcription factor 2.
   
 0.908
FOXO3
Forkhead box O3.
    
 0.859
ENSSARP00000001878
annotation not available
    
 
 0.858
ENSSARP00000010428
annotation not available
    
 0.844
MAPK1
Mitogen-activated protein kinase 1.
    
 0.844
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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