Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NECTIN1Nectin cell adhesion molecule 1. (485 aa)    
Predicted Functional Partners:
NECTIN3
Nectin cell adhesion molecule 3.
    
0.999
NECTIN2
Nectin cell adhesion molecule 2.
   
0.971
PARD3
Par-3 family cell polarity regulator.
    
 0.929
PRNP
Prion protein.
    
 
 0.819
ENSSARP00000001712
annotation not available
    
   0.783
CASK
Calcium/calmodulin dependent serine protein kinase.
    
 0.706
ENSSARP00000003035
annotation not available
    
 0.665
ENSSARP00000001171
annotation not available
    
 0.631
SKAP1
Src kinase associated phosphoprotein 1.
     
 0.620
ENSSARP00000002856
annotation not available
      
 0.616
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.