Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NUCKS1Nuclear casein kinase and cyclin dependent kinase substrate 1. (237 aa)    
Predicted Functional Partners:
PHAX
Phosphorylated adaptor for RNA export.
    
   0.944
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
    
   0.783
SLC41A1
Solute carrier family 41 member 1.
 
    
 0.717
ENSSARP00000001975
annotation not available
      
 0.698
PM20D1
Peptidase M20 domain containing 1.
      
 0.687
ENSSARP00000011033
annotation not available
      
 0.618
COMP
Cartilage oligomeric matrix protein.
    
 
 0.610
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
      
 0.604
WDHD1
WD repeat and HMG-box DNA binding protein 1.
      
 0.601
CPA3
Carboxypeptidase A3.
   
  
 0.595
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (12%) [HD]