REV1 protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

REV1

REV1 DNA directed polymerase. (1229 aa)

Predicted Functional Partners:

REV3L

0.997

POLK

0.996

ENSSARP00000003677

0.991

POLH

0.991

POLI

0.988

RAD51

0.969

ENSSARP00000000898

0.965

UBA52

0.965

ENSSARP00000004100

0.965

POLD2

0.958

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

Export your current network:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSARP00000000898	ENSSARP00000003677	ENSSARP00000000898	ENSSARP00000003677	annotation not available	annotation not available	0.993
ENSSARP00000000898	ENSSARP00000004100	ENSSARP00000000898	ENSSARP00000004100	annotation not available	annotation not available	0.496
ENSSARP00000000898	POLD2	ENSSARP00000000898	ENSSARP00000005855	annotation not available	DNA polymerase delta 2, accessory subunit.	0.999
ENSSARP00000000898	POLH	ENSSARP00000000898	ENSSARP00000009109	annotation not available	DNA polymerase eta.	0.672
ENSSARP00000000898	POLK	ENSSARP00000000898	ENSSARP00000006881	annotation not available	DNA polymerase kappa.	0.482
ENSSARP00000000898	RAD51	ENSSARP00000000898	ENSSARP00000002591	annotation not available	RAD51 recombinase.	0.686
ENSSARP00000000898	REV1	ENSSARP00000000898	ENSSARP00000001966	annotation not available	REV1 DNA directed polymerase.	0.965
ENSSARP00000000898	REV3L	ENSSARP00000000898	ENSSARP00000009934	annotation not available	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.994
ENSSARP00000000898	UBA52	ENSSARP00000000898	ENSSARP00000000901	annotation not available	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.472
ENSSARP00000003677	ENSSARP00000000898	ENSSARP00000003677	ENSSARP00000000898	annotation not available	annotation not available	0.993
ENSSARP00000003677	ENSSARP00000004100	ENSSARP00000003677	ENSSARP00000004100	annotation not available	annotation not available	0.984
ENSSARP00000003677	POLD2	ENSSARP00000003677	ENSSARP00000005855	annotation not available	DNA polymerase delta 2, accessory subunit.	0.994
ENSSARP00000003677	POLH	ENSSARP00000003677	ENSSARP00000009109	annotation not available	DNA polymerase eta.	0.992
ENSSARP00000003677	POLI	ENSSARP00000003677	ENSSARP00000007807	annotation not available	DNA polymerase iota.	0.987
ENSSARP00000003677	POLK	ENSSARP00000003677	ENSSARP00000006881	annotation not available	DNA polymerase kappa.	0.981
ENSSARP00000003677	RAD51	ENSSARP00000003677	ENSSARP00000002591	annotation not available	RAD51 recombinase.	0.982
ENSSARP00000003677	REV1	ENSSARP00000003677	ENSSARP00000001966	annotation not available	REV1 DNA directed polymerase.	0.991
ENSSARP00000003677	REV3L	ENSSARP00000003677	ENSSARP00000009934	annotation not available	REV3 like, DNA directed polymerase zeta catalytic subunit.	0.980
ENSSARP00000003677	UBA52	ENSSARP00000003677	ENSSARP00000000901	annotation not available	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.980
ENSSARP00000004100	ENSSARP00000000898	ENSSARP00000004100	ENSSARP00000000898	annotation not available	annotation not available	0.496