PBRM1 protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PBRM1

Polybromo 1. (1689 aa)

Predicted Functional Partners:

SMARCE1

0.999

SMARCB1

0.999

SMARCD1

0.999

ARID2

0.999

PHF10

0.998

SMARCC1

0.998

SMARCD2

0.998

ACTL6B

0.997

ENSSARP00000004979

0.997

ACTL6A

0.997

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL6A	ACTL6B	ENSSARP00000012646	ENSSARP00000004202	Actin like 6A.	Actin like 6B.	0.901
ACTL6A	ARID2	ENSSARP00000012646	ENSSARP00000006767	Actin like 6A.	AT-rich interaction domain 2.	0.996
ACTL6A	ENSSARP00000004979	ENSSARP00000012646	ENSSARP00000004979	Actin like 6A.	annotation not available	0.998
ACTL6A	PBRM1	ENSSARP00000012646	ENSSARP00000001974	Actin like 6A.	Polybromo 1.	0.997
ACTL6A	PHF10	ENSSARP00000012646	ENSSARP00000000294	Actin like 6A.	PHD finger protein 10.	0.997
ACTL6A	SMARCB1	ENSSARP00000012646	ENSSARP00000003361	Actin like 6A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1.	0.999
ACTL6A	SMARCC1	ENSSARP00000012646	ENSSARP00000003245	Actin like 6A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1.	0.996
ACTL6A	SMARCD1	ENSSARP00000012646	ENSSARP00000004042	Actin like 6A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1.	0.998
ACTL6A	SMARCD2	ENSSARP00000012646	ENSSARP00000008974	Actin like 6A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2.	0.998
ACTL6A	SMARCE1	ENSSARP00000012646	ENSSARP00000000388	Actin like 6A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.998
ACTL6B	ACTL6A	ENSSARP00000004202	ENSSARP00000012646	Actin like 6B.	Actin like 6A.	0.901
ACTL6B	ARID2	ENSSARP00000004202	ENSSARP00000006767	Actin like 6B.	AT-rich interaction domain 2.	0.996
ACTL6B	ENSSARP00000004979	ENSSARP00000004202	ENSSARP00000004979	Actin like 6B.	annotation not available	0.998
ACTL6B	PBRM1	ENSSARP00000004202	ENSSARP00000001974	Actin like 6B.	Polybromo 1.	0.997
ACTL6B	PHF10	ENSSARP00000004202	ENSSARP00000000294	Actin like 6B.	PHD finger protein 10.	0.997
ACTL6B	SMARCB1	ENSSARP00000004202	ENSSARP00000003361	Actin like 6B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1.	0.999
ACTL6B	SMARCC1	ENSSARP00000004202	ENSSARP00000003245	Actin like 6B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1.	0.996
ACTL6B	SMARCD1	ENSSARP00000004202	ENSSARP00000004042	Actin like 6B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1.	0.998
ACTL6B	SMARCD2	ENSSARP00000004202	ENSSARP00000008974	Actin like 6B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2.	0.998
ACTL6B	SMARCE1	ENSSARP00000004202	ENSSARP00000000388	Actin like 6B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1.	0.998