STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLE2DNA polymerase epsilon 2, accessory subunit. (528 aa)    
Predicted Functional Partners:
POLE
DNA polymerase epsilon, catalytic subunit.
   
 0.999
ENSSARP00000004694
annotation not available
   
 
 0.999
POLD2
DNA polymerase delta 2, accessory subunit.
   
 
 0.999
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
   
 0.998
POLA1
DNA polymerase alpha 1, catalytic subunit.
   
 0.997
ENSSARP00000006215
annotation not available
   
 0.997
ENSSARP00000001769
annotation not available
   
 0.996
MCM4
Minichromosome maintenance complex component 4.
   
 0.996
CDC45
Cell division cycle 45.
   
 0.996
ENSSARP00000003872
annotation not available
   
 0.994
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.