Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SGMS2Sphingomyelin synthase 2. (365 aa)    
Predicted Functional Partners:
SMPD2
Sphingomyelin phosphodiesterase 2.
     
 0.977
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 
 0.958
UGCG
UDP-glucose ceramide glucosyltransferase.
     
 0.956
ASAH1
N-acylsphingosine amidohydrolase 1.
     
 0.951
CERS2
Ceramide synthase 2.
     
 0.943
ACER2
Alkaline ceramidase 2.
     
 0.939
DEGS2
Delta 4-desaturase, sphingolipid 2.
   
 
 0.938
PLPP1
Phospholipid phosphatase 1.
     
 0.925
SGPP1
Sphingosine-1-phosphate phosphatase 1.
     
 0.924
CERS6
Ceramide synthase 6.
     
 0.923
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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