Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SORT1Sortilin 1. (827 aa)    
Predicted Functional Partners:
NGF
Nerve growth factor.
    
 
 0.981
ENSSARP00000009500
annotation not available
    
 
 0.977
BDNF
Brain derived neurotrophic factor.
    
 
 0.975
SORCS1
Sortilin related VPS10 domain containing receptor 1.
    
 
 0.969
NTRK2
Neurotrophic receptor tyrosine kinase 2.
    
 
 0.928
ENSSARP00000005021
annotation not available
    
 
 0.901
PSAP
Prosaposin.
    
 
 0.896
SORCS3
Sortilin related VPS10 domain containing receptor 3.
    
 
 0.895
NTF3
Neurotrophin 3.
    
 
 0.863
ENSSARP00000004844
annotation not available
    
 0.754
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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