Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL1R2Interleukin 1 receptor type 2. (372 aa)    
Predicted Functional Partners:
ENSSARP00000003676
annotation not available
   
 0.991
IL1A
Interleukin 1 alpha.
    
 0.980
ENSSARP00000001078
annotation not available
   
 
 0.957
EXOC6B
Exocyst complex component 6B.
    
   0.892
IL1RN
Interleukin 1 receptor antagonist.
   
 0.860
ENSSARP00000006231
annotation not available
    
   0.826
EXOC6
Exocyst complex component 6.
    
   0.799
ENSSARP00000012716
annotation not available
    
   0.795
EXOC4
Exocyst complex component 4.
    
   0.789
ENSSARP00000010660
annotation not available
    
 0.768
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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