Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C5orf46Chromosome 5 open reading frame 46. (88 aa)    
Predicted Functional Partners:
LYPD4
LY6/PLAUR domain containing 4.
  
     0.507
ENSSARP00000003946
annotation not available
  
     0.471
ENSSARP00000006335
annotation not available
  
    0.465
FAM107B
Family with sequence similarity 107 member B.
      
 0.461
ENSSARP00000010955
annotation not available
      
 0.461
ENSSARP00000005166
annotation not available
      
 0.450
SSMEM1
Serine rich single-pass membrane protein 1.
  
     0.428
BPIFA1
BPI fold containing family A member 1.
  
     0.416
ENSSARP00000001307
annotation not available
  
     0.414
SYNPO2
Synaptopodin 2.
  
     0.413
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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