Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POC1APOC1 centriolar protein A. (406 aa)    
Predicted Functional Partners:
POC1B
POC1 centriolar protein B.
   
   0.948
CORO1A
Coronin 1A.
   
   0.945
WDR82
WD repeat domain 82.
  
 
 0.907
RBBP5
RB binding protein 5, histone lysine methyltransferase complex subunit.
   
 0.875
ASH2L
ASH2 like, histone lysine methyltransferase complex subunit.
    
 0.874
ENSSARP00000005058
annotation not available
    
 0.874
CXXC1
CXXC finger protein 1.
    
 0.873
KAT2B
Lysine acetyltransferase 2B.
    
 0.851
KAT14
Lysine acetyltransferase 14.
    
  0.833
YEATS2
YEATS domain containing 2.
    
  0.825
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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