STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBR4Ubiquitin protein ligase E3 component n-recognin 4. (5120 aa)    
Predicted Functional Partners:
KCMF1
Potassium channel modulatory factor 1.
    
 
 0.969
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.
   
 
 0.815
UBR1
Ubiquitin protein ligase E3 component n-recognin 1.
   
  
 0.814
UBR2
Ubiquitin protein ligase E3 component n-recognin 2.
   
  
 0.804
ENSSARP00000008009
annotation not available
   
 
 0.774
GCN1
GCN1 activator of EIF2AK4.
   
  
 0.714
CUL9
Cullin 9.
     
 0.690
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.682
ENSSARP00000003935
annotation not available
   
  
 0.680
ENSSARP00000002492
annotation not available
   
 
 0.677
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.