Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SP2Sp2 transcription factor. (587 aa)    
Predicted Functional Partners:
WAC
WW domain containing adaptor with coiled-coil.
    
 0.650
ZNF263
Zinc finger protein 263.
    
 
 0.624
ALOX5
Arachidonate 5-lipoxygenase.
    
 
 0.612
MYSM1
Myb like, SWIRM and MPN domains 1.
    
  0.611
RS1
Retinoschisin 1.
    
 
 0.597
ENSSARP00000006823
annotation not available
    
 0.567
KDM2A
Lysine demethylase 2A.
    
 0.521
ENSSARP00000007374
annotation not available
    
 0.521
TFB2M
Transcription factor B2, mitochondrial.
    
 0.507
RP2
RP2 activator of ARL3 GTPase.
    
 
 0.495
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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