AIFM1 protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

AIFM1

Apoptosis inducing factor mitochondria associated 1. (613 aa)

Predicted Functional Partners:

LOC101541112

0.907

PPIA

0.907

MACROH2A1

0.882

MACROH2A2

0.882

BAX

0.872

ENSSARP00000003623

0.865

SUOX

0.864

CYB5R4

0.855

ENSSARP00000000836

0.830

FDX1

0.830

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIFM1	BAX	ENSSARP00000003252	ENSSARP00000010589	Apoptosis inducing factor mitochondria associated 1.	BCL2 associated X, apoptosis regulator.	0.872
AIFM1	CYB5R4	ENSSARP00000003252	ENSSARP00000011815	Apoptosis inducing factor mitochondria associated 1.	Cytochrome b5 reductase 4.	0.855
AIFM1	ENSSARP00000000836	ENSSARP00000003252	ENSSARP00000000836	Apoptosis inducing factor mitochondria associated 1.	annotation not available	0.830
AIFM1	ENSSARP00000003623	ENSSARP00000003252	ENSSARP00000003623	Apoptosis inducing factor mitochondria associated 1.	annotation not available	0.865
AIFM1	FDX1	ENSSARP00000003252	ENSSARP00000012964	Apoptosis inducing factor mitochondria associated 1.	Ferredoxin 1.	0.830
AIFM1	LOC101541112	ENSSARP00000003252	ENSSARP00000004672	Apoptosis inducing factor mitochondria associated 1.	Peptidyl-prolyl cis-trans isomerase A.	0.907
AIFM1	MACROH2A1	ENSSARP00000003252	ENSSARP00000001320	Apoptosis inducing factor mitochondria associated 1.	macroH2A.1 histone.	0.882
AIFM1	MACROH2A2	ENSSARP00000003252	ENSSARP00000007693	Apoptosis inducing factor mitochondria associated 1.	macroH2A.2 histone.	0.882
AIFM1	PPIA	ENSSARP00000003252	ENSSARP00000006562	Apoptosis inducing factor mitochondria associated 1.	Peptidylprolyl isomerase A.	0.907
AIFM1	SUOX	ENSSARP00000003252	ENSSARP00000005654	Apoptosis inducing factor mitochondria associated 1.	Sulfite oxidase.	0.864
BAX	AIFM1	ENSSARP00000010589	ENSSARP00000003252	BCL2 associated X, apoptosis regulator.	Apoptosis inducing factor mitochondria associated 1.	0.872
BAX	LOC101541112	ENSSARP00000010589	ENSSARP00000004672	BCL2 associated X, apoptosis regulator.	Peptidyl-prolyl cis-trans isomerase A.	0.728
BAX	PPIA	ENSSARP00000010589	ENSSARP00000006562	BCL2 associated X, apoptosis regulator.	Peptidylprolyl isomerase A.	0.728
CYB5R4	AIFM1	ENSSARP00000011815	ENSSARP00000003252	Cytochrome b5 reductase 4.	Apoptosis inducing factor mitochondria associated 1.	0.855
CYB5R4	ENSSARP00000000836	ENSSARP00000011815	ENSSARP00000000836	Cytochrome b5 reductase 4.	annotation not available	0.801
CYB5R4	FDX1	ENSSARP00000011815	ENSSARP00000012964	Cytochrome b5 reductase 4.	Ferredoxin 1.	0.801
CYB5R4	SUOX	ENSSARP00000011815	ENSSARP00000005654	Cytochrome b5 reductase 4.	Sulfite oxidase.	0.953
ENSSARP00000000836	AIFM1	ENSSARP00000000836	ENSSARP00000003252	annotation not available	Apoptosis inducing factor mitochondria associated 1.	0.830
ENSSARP00000000836	CYB5R4	ENSSARP00000000836	ENSSARP00000011815	annotation not available	Cytochrome b5 reductase 4.	0.801
ENSSARP00000000836	SUOX	ENSSARP00000000836	ENSSARP00000005654	annotation not available	Sulfite oxidase.	0.805