Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C12orf4Chromosome 12 open reading frame 4. (466 aa)    
Predicted Functional Partners:
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
    
 
 0.984
TBCK
TBC1 domain containing kinase.
    
 
 0.978
TBC1D31
TBC1 domain family member 31.
    
 
 0.851
RTN4IP1
Reticulon 4 interacting protein 1.
   
   0.838
CENPJ
Centromere protein J.
    
   0.631
ENSSARP00000000975
annotation not available
      
 0.617
SF3B3
Splicing factor 3b subunit 3.
      
 0.515
ENSSARP00000012213
annotation not available
      
 0.502
ENSSARP00000008317
annotation not available
    
   0.496
ENSSARP00000012258
annotation not available
    
   0.496
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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