STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C12orf4Chromosome 12 open reading frame 4. (466 aa)    
Predicted Functional Partners:
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
    
 
 0.646
TBCK
TBC1 domain containing kinase.
    
 
 0.645
ENSSARP00000012213
annotation not available
      
 0.577
ENSSARP00000004085
annotation not available
      
 0.540
ENSSARP00000011488
annotation not available
      
 0.540
PRICKLE1
Prickle planar cell polarity protein 1.
      
 0.537
TBC1D31
TBC1 domain family member 31.
    
 
 0.531
ENSSARP00000008222
annotation not available
      
 0.529
FGD6
FYVE, RhoGEF and PH domain containing 6.
      
 0.509
SCN8A
Sodium voltage-gated channel alpha subunit 8.
      
 0.499
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.