Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000003522annotation not available (1106 aa)    
Predicted Functional Partners:
GFRA1
GDNF family receptor alpha 1.
    
 0.998
GFRA3
GDNF family receptor alpha 3.
    
 0.988
GRB2
Growth factor receptor bound protein 2.
    
 0.976
PLCG1
Phospholipase C gamma 1.
    
 0.965
STAT3
Signal transducer and activator of transcription 3.
    
 0.964
GRB10
Growth factor receptor bound protein 10.
    
  0.962
GDNF
Glial cell derived neurotrophic factor.
    
 0.960
EGFR
Epidermal growth factor receptor.
    
 0.959
ENSSARP00000002690
annotation not available
    
 0.958
CBL
Cbl proto-oncogene.
    
 0.953
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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