STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESR2Estrogen receptor 2. (530 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator 1.
    
 0.992
ESR1
Estrogen receptor 1.
    
0.991
NCOA3
Nuclear receptor coactivator 3.
    
 0.971
NCOA2
Nuclear receptor coactivator 2.
    
 0.968
PTGES3
Prostaglandin E synthase 3.
   
 0.956
MED1
Mediator complex subunit 1.
    
 0.944
NCOR1
Nuclear receptor corepressor 1.
    
 0.934
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
    
 0.926
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
     
 0.914
NCOA5
Nuclear receptor coactivator 5.
    
 
 0.910
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.