MBD4 protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

MBD4

methyl-CpG binding domain 4, DNA glycosylase. (575 aa)

Predicted Functional Partners:

MLH1

0.960

ENSSARP00000003918

0.896

ENSSARP00000007409

0.894

MTA2

0.872

ENSSARP00000012680

0.872

ENSSARP00000003075

0.868

RBBP7

0.868

MPG

0.845

ENSSARP00000010801

0.831

KANSL3

0.831

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSARP00000003075	ENSSARP00000003918	ENSSARP00000003075	ENSSARP00000003918	annotation not available	annotation not available	0.961
ENSSARP00000003075	ENSSARP00000007409	ENSSARP00000003075	ENSSARP00000007409	annotation not available	annotation not available	0.983
ENSSARP00000003075	ENSSARP00000012680	ENSSARP00000003075	ENSSARP00000012680	annotation not available	annotation not available	0.991
ENSSARP00000003075	MBD4	ENSSARP00000003075	ENSSARP00000004075	annotation not available	methyl-CpG binding domain 4, DNA glycosylase.	0.868
ENSSARP00000003075	MTA2	ENSSARP00000003075	ENSSARP00000004346	annotation not available	Metastasis associated 1 family member 2.	0.989
ENSSARP00000003075	RBBP7	ENSSARP00000003075	ENSSARP00000007313	annotation not available	RB binding protein 7, chromatin remodeling factor.	0.931
ENSSARP00000003918	ENSSARP00000003075	ENSSARP00000003918	ENSSARP00000003075	annotation not available	annotation not available	0.961
ENSSARP00000003918	ENSSARP00000007409	ENSSARP00000003918	ENSSARP00000007409	annotation not available	annotation not available	0.828
ENSSARP00000003918	ENSSARP00000012680	ENSSARP00000003918	ENSSARP00000012680	annotation not available	annotation not available	0.887
ENSSARP00000003918	MBD4	ENSSARP00000003918	ENSSARP00000004075	annotation not available	methyl-CpG binding domain 4, DNA glycosylase.	0.896
ENSSARP00000003918	MTA2	ENSSARP00000003918	ENSSARP00000004346	annotation not available	Metastasis associated 1 family member 2.	0.887
ENSSARP00000003918	RBBP7	ENSSARP00000003918	ENSSARP00000007313	annotation not available	RB binding protein 7, chromatin remodeling factor.	0.961
ENSSARP00000007409	ENSSARP00000003075	ENSSARP00000007409	ENSSARP00000003075	annotation not available	annotation not available	0.983
ENSSARP00000007409	ENSSARP00000003918	ENSSARP00000007409	ENSSARP00000003918	annotation not available	annotation not available	0.828
ENSSARP00000007409	ENSSARP00000012680	ENSSARP00000007409	ENSSARP00000012680	annotation not available	annotation not available	0.996
ENSSARP00000007409	MBD4	ENSSARP00000007409	ENSSARP00000004075	annotation not available	methyl-CpG binding domain 4, DNA glycosylase.	0.894
ENSSARP00000007409	MTA2	ENSSARP00000007409	ENSSARP00000004346	annotation not available	Metastasis associated 1 family member 2.	0.996
ENSSARP00000007409	RBBP7	ENSSARP00000007409	ENSSARP00000007313	annotation not available	RB binding protein 7, chromatin remodeling factor.	0.981
ENSSARP00000010801	MBD4	ENSSARP00000010801	ENSSARP00000004075	annotation not available	methyl-CpG binding domain 4, DNA glycosylase.	0.831
ENSSARP00000012680	ENSSARP00000003075	ENSSARP00000012680	ENSSARP00000003075	annotation not available	annotation not available	0.991