Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000004292annotation not available (1210 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.974
KIT
KIT proto-oncogene, receptor tyrosine kinase.
    
 
 0.970
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.
    
 0.959
CBL
Cbl proto-oncogene.
    
 
 0.949
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.949
ENSSARP00000000693
annotation not available
    
   0.944
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.848
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.845
FER
FER tyrosine kinase.
    
  0.819
PTPN1
Protein tyrosine phosphatase non-receptor type 1.
    
   0.806
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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