Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NF2Neurofibromin 2. (617 aa)    
Predicted Functional Partners:
LATS1
Large tumor suppressor kinase 1.
    
 
 0.978
LATS2
Large tumor suppressor kinase 2.
    
 
 0.977
AMOT
Angiomotin.
    
 0.974
ENSSARP00000008568
annotation not available
    
 0.970
DCAF1
DDB1 and CUL4 associated factor 1.
    
 
 0.959
ENSSARP00000009427
annotation not available
    
 
 0.953
EGFR
Epidermal growth factor receptor.
    
 
 0.944
MED28
Mediator complex subunit 28.
    
 
 0.940
YAP1
Yes associated protein 1.
   
 0.906
ENSSARP00000008088
annotation not available
    
 0.899
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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