Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDC25ACell division cycle 25A. (338 aa)    
Predicted Functional Partners:
PLK1
Polo like kinase 1.
   
 0.997
CCNE1
Cyclin E1.
   
 0.995
CCNB2
Cyclin B2.
   
 0.991
CDK6
Cyclin dependent kinase 6.
   
 0.987
CCNE2
Cyclin E2.
   
 0.987
CDK4
Cyclin dependent kinase 4.
   
 0.987
ENSSARP00000011082
annotation not available
   
 0.983
CDK1
Cyclin dependent kinase 1.
   
 0.981
ENSSARP00000004303
annotation not available
   
 0.972
ENSSARP00000008600
annotation not available
   
 0.971
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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