Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000004844annotation not available (751 aa)    
Predicted Functional Partners:
APOE
Apolipoprotein E.
    
 0.996
BACE1
Beta-secretase 1.
    
 0.995
APLP2
Amyloid beta precursor like protein 2.
   
  0.993
ENSSARP00000010315
annotation not available
    
 
 0.992
ENSSARP00000008193
annotation not available
    
 
 0.986
PRNP
Prion protein.
   
 0.984
APBB1
Amyloid beta precursor protein binding family B member 1.
    
 0.981
ACHE
Acetylcholinesterase (Cartwright blood group).
    
 0.978
APBB2
Amyloid beta precursor protein binding family B member 2.
    
 0.976
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 
 0.970
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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