Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FOXO3Forkhead box O3. (466 aa)    
Predicted Functional Partners:
AKT2
AKT serine/threonine kinase 2.
    
 0.994
SIRT1
Sirtuin 1.
    
 0.994
CREBBP
CREB binding protein.
   
 0.992
YWHAG
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma.
    
 0.991
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.989
YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta.
    
 0.988
ENSSARP00000001996
annotation not available
    
 0.987
ENSSARP00000008364
annotation not available
    
 0.986
FOXO4
Forkhead box O4.
    
0.985
USP7
Ubiquitin specific peptidase 7.
   
 0.985
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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