Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL1RNInterleukin 1 receptor antagonist. (179 aa)    
Predicted Functional Partners:
ENSSARP00000000939
annotation not available
    
 0.954
IL1R1
Interleukin 1 receptor type 1.
    
 0.954
IL1R2
Interleukin 1 receptor type 2.
   
 0.860
IL6
Interleukin 6.
   
  
 0.830
IL10
Interleukin 10.
    
 0.801
ENSSARP00000007030
annotation not available
      
 0.748
IL1A
Interleukin 1 alpha.
   
  
 0.688
ENSSARP00000003676
annotation not available
   
  
 0.677
ENSSARP00000004590
annotation not available
   
  
 0.670
CX3CR1
C-X3-C motif chemokine receptor 1.
   
  
 0.660
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (38%) [HD]