STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXO4Forkhead box O4. (508 aa)    
Predicted Functional Partners:
AKT2
AKT serine/threonine kinase 2.
    
 0.966
ENSSARP00000001996
annotation not available
    
 0.966
AKT3
AKT serine/threonine kinase 3.
    
 0.966
ENSSARP00000010757
annotation not available
    
 0.961
SIRT1
Sirtuin 1.
    
 0.955
USP7
Ubiquitin specific peptidase 7.
   
 0.940
ENSSARP00000002717
annotation not available
    
 0.925
SGK1
Serum/glucocorticoid regulated kinase 1.
    
 0.925
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.905
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.905
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.