STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (234 aa)    
Predicted Functional Partners:
SMC5
Structural maintenance of chromosomes 5.
    
 0.999
ENSSARP00000011914
annotation not available
    
 0.999
SMC6
Structural maintenance of chromosomes 6.
    
 0.999
ENSSARP00000001575
annotation not available
    
 0.969
MAGEB18
MAGE family member B18.
    
 0.966
RANBP2
RAN binding protein 2.
     
 0.940
SMC3
Structural maintenance of chromosomes 3.
    
 0.937
ENSSARP00000005166
annotation not available
   
 0.934
ENSSARP00000001030
annotation not available
    
 0.908
ENSSARP00000006430
annotation not available
    
 0.908
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.