STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLIS3GLIS family zinc finger 3. (775 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.977
ENSSARP00000007129
annotation not available
    
 0.928
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.910
ENSSARP00000001028
annotation not available
   
 0.903
SPOP
Speckle type BTB/POZ protein.
   
 0.903
ENSSARP00000010204
annotation not available
    
 0.889
ENSSARP00000011952
annotation not available
    
 0.889
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
    
 0.827
CUL3
Cullin 3.
    
 0.811
GSK3B
Glycogen synthase kinase 3 beta.
    
 0.785
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.