STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AHY45320.1BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (149 aa)    
Predicted Functional Partners:
AHY47153.1
Carboxyl transferase domain; COG:COG0777: Acetyl-CoA carboxylase beta subunit [Lipid metabolism]; Pfam:PF01039:Carboxyl transferase; PRINTS:PR01070:Acetyl-CoA carboxylase carboxyl transferase, beta subunit; ProSiteProfiles:PS50989:Acetyl-coenzyme A carboxyltransferase, C-terminal; SUPERFAMILY:SSF52096:No Description;MetaCyc: PWY-5744; UniPathway: UPA00655.
 
 0.995
AHY45321.1
accC: acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.994
accA
accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.992
AHY46201.1
accC: acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.975
fabH
fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.973
AHY45737.1
COG:COG4770: Acetyl/propionyl-CoA carboxylase alpha subunit [Lipid metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50968:Biotin/lipoyl attachment; SMART:SM00878:Biotin carboxylase, C-terminal; SUPERFAMILY:SSF56059:No Description.
 
 0.971
AHY46668.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; PIRSF:PIRSF000446:Malonyl CoA-acyl carrier protein transacylase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
 
 
 0.950
AHY45525.1
COG:COG0331: (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Pfam:PF00698:Acyl transferase; Pfam:PF00698:Acyl transferase; SMART:SM00827:Polyketide synthase, acyl transferase domain; SUPERFAMILY:SSF52151:Acyl transferase/acyl hydrolase/lysophospholipase.
  
 
 0.944
AHY46205.1
Biotin-requiring enzyme; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 
0.916
AHY47138.1
TIGRFAM:TIGR01344:Malate synthase A; COG:COG2225: Malate synthase [Energy production and conversion]; Pfam:PF01274:Malate synthase; PIRSF:PIRSF001363:Malate synthase A; ProSitePatterns:PS00510:Malate synthase, conserved site; SUPERFAMILY:SSF51645:Malate synthase-like;KEGG: 00620; KEGG: 00630; UniPathway: UPA00703; malate_syn_A; Belongs to the malate synthase family.
     
 0.903
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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