STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
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[Homology]
Score
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (364 aa)    
Predicted Functional Partners:
AHY45341.1
COG:COG0021: Transketolase [Carbohydrate transport and metabolism]; Pfam:PF00456:Transketolase, N-terminal; Pfam:PF00456:Transketolase, N-terminal; ProSitePatterns:PS00802:Transketolase binding site; SMART:SM00861:Transketolase-like, pyrimidine-binding domain; SUPERFAMILY:SSF52518:No Description.
 
 0.999
AHY46395.1
Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.939
AHY47740.1
TIGRFAM:TIGR00167:Ketose-bisphosphate aldolase, class-II; COG:COG0191: Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Pfam:PF01116:Ketose-bisphosphate aldolase, class-II; PIRSF:PIRSF001359:Ketose-bisphosphate aldolase, class-II; SUPERFAMILY:SSF51569:No Description.
  
 
 0.939
tpiA
Tim: triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.938
eno
Eno: phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.937
AHY46881.1
COG:COG1494: Fructose-16-bisphosphatase/sedoheptulose 17-bisphosphatase and related proteins [Carbohydrate transport and metabolism]; Pfam:PF03320:Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; Pfam:PF03320:Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; PIRSF:PIRSF004532:Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase; SUPERFAMILY:SSF56655:No Description; Belongs to the FBPase class 2 family.
    
 0.936
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.931
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 
 0.931
AHY45693.1
COG:COG3588: Fructose-16-bisphosphate aldolase [Carbohydrate transport and metabolism]; Pfam:PF00274:Fructose-bisphosphate aldolase, class-I; Pfam:PF00274:Fructose-bisphosphate aldolase, class-I; SUPERFAMILY:SSF51569:No Description.
   
 0.929
AHY47066.1
TIGRFAM:TIGR01534:Glyceraldehyde-3-phosphate dehydrogenase, type I; COG:COG0057: Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Pfam:PF02800:Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PIRSF:PIRSF000149:Glyceraldehyde/Erythrose phosphate dehydrogenase family; PRINTS:PR00078:Glyceraldehyde/Erythrose phosphate dehydrogenase family; ProSitePatterns:PS00071:Glyceraldehyde 3-phosphate dehydrogenase, active site; SMART:SM00846:Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SUPERFAMILY:SSF [...]
  
 
 0.924
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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