STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45350.1TIGRFAM:TIGR02033:Hydantoinase/dihydropyrimidinase; COG:COG0044: Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Pfam:PF13147:Amidohydrolase; SUPERFAMILY:SSF51556:No Description;Reactome: REACT_18266. (463 aa)    
Predicted Functional Partners:
AHY45353.1
NCS1 nucleoside transporter family; TIGRFAM:TIGR00800:Nucleobase cation symporter-1, NCS1; COG:COG1953: Cytosine/uracil/thiamine/allantoin permeases [Nucleotide transport and metabolism / Coenzyme metabolism]; Pfam:PF02133:Permease, cytosine/purines, uracil, thiamine, allantoin.
 
  
 0.930
pyrB
TIGRFAM:TIGR00670:Aspartate carbamoyltransferase; COG:COG0540: Aspartate carbamoyltransferase catalytic chain [Nucleotide transport and metabolism]; Pfam:PF02729:Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Hamap:MF_00001:Aspartate carbamoyltransferase; PRINTS:PR00101:Aspartate carbamoyltransferase; ProSitePatterns:PS00097:Aspartate/ornithine carbamoyltransferase; SUPERFAMILY:SSF53671:Aspartate/ornithine carbamoyltransferase;KEGG: 00240; KEGG: 00250; MetaCyc: PWY-5686; UniPathway: UPA00070; asp_carb_tr; Belongs to the aspartate/ornithine carbamoyltransferase superfami [...]
 
 0.927
AHY45352.1
TIGRFAM:TIGR01879:Amidase, hydantoinase/carbamoylase; COG:COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Pfam:PF01546:Peptidase M20; PIRSF:PIRSF001235:Amidase, hydantoinase/carbamoylase; SUPERFAMILY:SSF53187:No Description.
 
  
 0.825
carB
TIGRFAM:TIGR01369:Carbamoyl-phosphate synthase, large subunit; COG:COG0458: Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF02786:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; Hamap:MF_01210_B:Carbamoyl-phosphate synthase, large subunit; PRINTS:PR00098:Carbamoyl-phosphate synthase large subunit, CPSase domain; ProSitePatterns:PS00866:Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain; ProSiteProfiles:PS50975:ATP-grasp fold; SMART:SM01096:Carbamoyl [...]
 
 
 0.825
AHY45354.1
F420-dependent oxidoreductase, CPS_4043 family; TIGRFAM:TIGR03842:F420-dependent oxidoreductase-predicted, CPS4043; COG:COG2141: Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Pfam:PF00296:Luciferase-like domain; SUPERFAMILY:SSF51679:Luciferase-like domain.
 
     0.815
carA
TIGRFAM:TIGR01368:Carbamoyl-phosphate synthase, small subunit; COG:COG0505: Carbamoylphosphate synthase small subunit [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Pfam:PF00988:Carbamoyl-phosphate synthase, small subunit N-terminal domain; Hamap:MF_01209:Carbamoyl-phosphate synthase, small subunit; PRINTS:PR00099:Carbamoyl-phosphate synthase protein GATase domain signature; ProSiteProfiles:PS51273:Glutamine amidotransferase; SMART:SM01097:Carbamoyl-phosphate synthase, small subunit N-terminal domain; SUPERFAMILY:SSF52317:No Description;KEGG: 00240; KEGG: [...]
 
  
 0.791
AHY45351.1
COG:COG0160: 4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Pfam:PF00202:Aminotransferase class-III; Pfam:PF00202:Aminotransferase class-III; PIRSF:PIRSF000521:No Description; ProSitePatterns:PS00600:Aminotransferase class-III; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.759
pyrR
Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.758
pyrD
Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.743
AHY46586.1
TIGRFAM:TIGR03173:Xanthine permease; COG:COG2233: Xanthine/uracil permeases [Nucleotide transport and metabolism]; Pfam:PF00860:Xanthine/uracil/vitamin C permease; ProSitePatterns:PS01116:Xanthine/uracil permease; SUPERFAMILY:SSF158694:No Description.
 
  
 0.716
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (30%) [HD]
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