STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45357.1TIGRFAM:TIGR01292:Thioredoxin reductase; COG:COG0492: Thioredoxin reductase [Posttranslational modification protein turnover chaperones]; Pfam:PF07992:Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; PRINTS:PR00469:Pyridine nucleotide-disulphide oxidoreductase, class-II; ProSitePatterns:PS00573:Pyridine nucleotide-disulphide oxidoreductase, class-II, active site; SUPERFAMILY:SSF51905:No Description;KEGG: 00240; TRX_reduct. (334 aa)    
Predicted Functional Partners:
AHY45802.1
TIGRFAM:TIGR01068:Thioredoxin; COG:COG3118: Thioredoxin domain-containing protein [Posttranslational modification protein turnover chaperones]; Pfam:PF00085:Thioredoxin domain; PIRSF:PIRSF000077:Thioredoxin; PRINTS:PR00421:Thioredoxin; ProSiteProfiles:PS51352:Thioredoxin-like fold; SUPERFAMILY:SSF52833:Thioredoxin-like fold; Belongs to the thioredoxin family.
 
 0.996
AHY46299.1
TIGRFAM:TIGR00476:Selenide water dikinase; COG:COG0709: Selenophosphate synthase [Amino acid transport and metabolism]; Pfam:PF02769:AIR synthase-related protein, C-terminal domain; SUPERFAMILY:SSF56042:AIR synthase-related protein, C-terminal domain;KEGG: 00450; MetaCyc: PWY-6281.
     
 0.916
AHY47651.1
Ferredoxin; COG:COG0633: Ferredoxin [Energy production and conversion]; Pfam:PF00111:2Fe-2S ferredoxin-type domain; Pfam:PF00111:2Fe-2S ferredoxin-type domain; ProSiteProfiles:PS51085:2Fe-2S ferredoxin-type domain; SUPERFAMILY:SSF54292:2Fe-2S ferredoxin-type domain.
   
 
 0.715
AHY45660.1
COG:COG0607: Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Pfam:PF00581:Rhodanese-like domain; Pfam:PF00581:Rhodanese-like domain; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF52821:Rhodanese-like domain.
  
  
 0.677
AHY47427.1
ThiF family; COG:COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 [Coenzyme metabolism]; Pfam:PF00899:UBA/THIF-type NAD/FAD binding fold; ProSiteProfiles:PS50206:Rhodanese-like domain; SMART:SM00450:Rhodanese-like domain; SUPERFAMILY:SSF69572:Molybdenum cofactor biosynthesis, MoeB.
  
  
 0.677
AHY47829.1
UvrD/REP helicase N-terminal domain; COG:COG0210: Superfamily I DNA and RNA helicases [DNA replication recombination and repair]; Pfam:PF00580:UvrD-like Helicase, ATP-binding domain; ProSiteProfiles:PS51217:DNA helicase, UvrD-like, C-terminal; SUPERFAMILY:SSF52540:P-loop containing nucleoside triphosphate hydrolase; Belongs to the helicase family. UvrD subfamily.
 
  
 0.626
AHY45431.1
COG:COG1225: Peroxiredoxin [Posttranslational modification protein turnover chaperones]; Pfam:PF00578:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Pfam:PF00578:Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; ProSiteProfiles:PS51352:Thioredoxin-like fold; SUPERFAMILY:SSF52833:Thioredoxin-like fold.
 
  
 0.615
metG
metG: methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.610
AHY45891.1
TIGRFAM:TIGR00229:PAS domain; COG:COG0642: Signal transduction histidine kinase [Signal transduction mechanisms]; Pfam:PF02518:Histidine kinase-like ATPase, ATP-binding domain; PRINTS:PR00344:Signal transduction histidine kinase-related protein, C-terminal; ProSiteProfiles:PS50112:PAS domain; SMART:SM00387:Histidine kinase-like ATPase, ATP-binding domain; SUPERFAMILY:SSF55874:Histidine kinase-like ATPase, ATP-binding domain; sensory_box.
 
  
 0.608
mnmA
trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.588
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.