STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAnadA: quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (327 aa)    
Predicted Functional Partners:
AHY45372.1
nadC: nicotinate-nucleotide diphosphorylase (carboxylating); TIGRFAM:TIGR00078:Nicotinate-nucleotide pyrophosphorylase; COG:COG0157: Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; PIRSF:PIRSF006250:Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD; SUPERFAMILY:SSF51690:Quinolinate phosphoribosyl transferase, C-terminal;KEGG: 00760; MetaCyc: PWY-5653; UniPathway: UPA00253; Belongs to the NadC/ModD family.
 
 0.999
AHY45373.1
COG:COG0029: Aspartate oxidase [Coenzyme metabolism]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; PRINTS:PR00368:FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SUPERFAMILY:SSF51905:No Description.
 0.999
AHY45374.1
COG:COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; PIRSF:PIRSF005572:Cysteine desulfurase, NifS; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
  
  
 0.859
valS
valS: valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
      0.642
nadE
nadE: NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.630
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.609
dapA
dapA: dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.581
AHY45296.1
COG:COG1053: Succinate dehydrogenase/fumarate reductase flavoprotein subunit [Energy production and conversion]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; SUPERFAMILY:SSF51905:No Description.
   
 0.556
AHY45668.1
Competence/damage-inducible protein CinA N-terminal domain; TIGRFAM:TIGR00200:Competence-induced protein CinA; COG:COG1058: Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Pfam:PF02464:CinA, C-terminal; Hamap:MF_00226_B:Competence-induced protein CinA; PIRSF:PIRSF006728:Competence-induced protein CinA; SMART:SM00852:Molybdopterin binding domain; SUPERFAMILY:SSF142433:No Description; cinA_nterm.
     
 0.542
nadD
TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.518
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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