STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHY45372.1nadC: nicotinate-nucleotide diphosphorylase (carboxylating); TIGRFAM:TIGR00078:Nicotinate-nucleotide pyrophosphorylase; COG:COG0157: Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; PIRSF:PIRSF006250:Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD; SUPERFAMILY:SSF51690:Quinolinate phosphoribosyl transferase, C-terminal;KEGG: 00760; MetaCyc: PWY-5653; UniPathway: UPA00253; Belongs to the NadC/ModD family. (297 aa)    
Predicted Functional Partners:
nadA
nadA: quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
AHY45373.1
COG:COG0029: Aspartate oxidase [Coenzyme metabolism]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; PRINTS:PR00368:FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SUPERFAMILY:SSF51905:No Description.
  
 0.999
AHY46527.1
COG:COG1488: Nicotinic acid phosphoribosyltransferase [Coenzyme metabolism]; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; Pfam:PF01729:Quinolinate phosphoribosyl transferase, C-terminal; PIRSF:PIRSF000484:Nicotinate phosphoribosyltransferase-related; SUPERFAMILY:SSF51690:Quinolinate phosphoribosyl transferase, C-terminal.
   
 0.961
AHY45668.1
Competence/damage-inducible protein CinA N-terminal domain; TIGRFAM:TIGR00200:Competence-induced protein CinA; COG:COG1058: Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Pfam:PF02464:CinA, C-terminal; Hamap:MF_00226_B:Competence-induced protein CinA; PIRSF:PIRSF006728:Competence-induced protein CinA; SMART:SM00852:Molybdopterin binding domain; SUPERFAMILY:SSF142433:No Description; cinA_nterm.
    
 0.955
nadD
TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.946
AHY45296.1
COG:COG1053: Succinate dehydrogenase/fumarate reductase flavoprotein subunit [Energy production and conversion]; Pfam:PF00890:FAD binding domain; Pfam:PF00890:FAD binding domain; SUPERFAMILY:SSF51905:No Description.
   
 0.936
surE
surE: 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.904
AHY47352.1
COG:COG2816: NTP pyrophosphohydrolases containing a Zn-finger probably nucleic-acid-binding [DNA replication recombination and repair]; Pfam:PF00293:NUDIX hydrolase domain; Pfam:PF00293:NUDIX hydrolase domain; ProSitePatterns:PS00893:NUDIX hydrolase, conserved site; ProSiteProfiles:PS51462:NUDIX hydrolase domain; SUPERFAMILY:SSF55811:NUDIX hydrolase domain-like.
     
 0.902
AHY45374.1
COG:COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; Pfam:PF00266:Aminotransferase, class V/Cysteine desulfurase; PIRSF:PIRSF005572:Cysteine desulfurase, NifS; SUPERFAMILY:SSF53383:Pyridoxal phosphate-dependent transferase.
  
  
 0.862
panB
panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     0.639
Your Current Organism:
Rubrobacter radiotolerans
NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1
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