AHY45401.1 protein (Rubrobacter radiotolerans)

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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AHY45401.1

Dass: transporter, divalent anion:Na+ symporter (DASS) family; TIGRFAM:TIGR00785:Sodium/sulphate symporter; COG:COG0471: Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Pfam:PF00939:Sodium/sulphate symporter; ProSitePatterns:PS01271:Sodium/sulphate symporter;Reactome: REACT_15518; Reactome: REACT_20633. (531 aa)

Predicted Functional Partners:

AHY45400.1

0.526

Your Current Organism:

Rubrobacter radiotolerans

NCBI taxonomy Id: 42256
Other names: ATCC 51242, Arthrobacter radiotolerans, CIP 106991, DSM 46359, DSM 5868, IAM 12072, IFO 14777, JCM 2153, NBRC 14777, R. radiotolerans, strain P-1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHY45400.1	AHY45401.1	RradSPS_0117	RradSPS_0118	Dass: transporter, divalent anion:Na+ symporter (DASS) family; TIGRFAM:TIGR00785:Sodium/sulphate symporter; COG:COG0471: Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Pfam:PF00939:Sodium/sulphate symporter; ProSitePatterns:PS01271:Sodium/sulphate symporter;Reactome: REACT_15518; Reactome: REACT_20633.	Dass: transporter, divalent anion:Na+ symporter (DASS) family; TIGRFAM:TIGR00785:Sodium/sulphate symporter; COG:COG0471: Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Pfam:PF00939:Sodium/sulphate symporter; ProSitePatterns:PS01271:Sodium/sulphate symporter;Reactome: REACT_15518; Reactome: REACT_20633.	0.526
AHY45401.1	AHY45400.1	RradSPS_0118	RradSPS_0117	Dass: transporter, divalent anion:Na+ symporter (DASS) family; TIGRFAM:TIGR00785:Sodium/sulphate symporter; COG:COG0471: Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Pfam:PF00939:Sodium/sulphate symporter; ProSitePatterns:PS01271:Sodium/sulphate symporter;Reactome: REACT_15518; Reactome: REACT_20633.	Dass: transporter, divalent anion:Na+ symporter (DASS) family; TIGRFAM:TIGR00785:Sodium/sulphate symporter; COG:COG0471: Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Pfam:PF00939:Sodium/sulphate symporter; ProSitePatterns:PS01271:Sodium/sulphate symporter;Reactome: REACT_15518; Reactome: REACT_20633.	0.526

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.867

expected number of edges:

13

PPI enrichment p-value:

0.000105

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006633

Fatty acid biosynthetic process

10 of 19

2.18

6.96

9.15e-18

GO:0032787

Monocarboxylic acid metabolic process

11 of 93

1.54

3.35

8.03e-15

GO:0071616

acyl-CoA biosynthetic process

3 of 9

1.99

1.69

0.00042

GO:2001295

malonyl-CoA biosynthetic process

2 of 3

2.29

1.29

0.0039

GO:0090407

Organophosphate biosynthetic process

6 of 121

1.16

1.17

9.69e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004312

Fatty acid synthase activity

5 of 9

2.21

3.27

2.20e-07

GO:0016747

Acyltransferase activity, transferring groups other than amino-acyl groups

7 of 62

1.51

2.23

2.20e-07

GO:0003989

acetyl-CoA carboxylase activity

3 of 4

2.34

1.98

0.00018

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

2 of 2

2.46

1.23

0.0054

GO:0016743

Carboxyl- or carbamoyltransferase activity

2 of 3

2.29

1.13

0.0080

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009317

acetyl-CoA carboxylase complex

3 of 4

2.34

2.03

0.00014

GO:1902494

Catalytic complex

4 of 76

1.18

0.9

0.0035

GO:0005737

Cytoplasm

11 of 938

0.53

0.46

0.00014

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:36584052

(2022) The inside scoop: Comparative genomics of two intranuclear bacteria, Candidatus Berkiella cookevillensis and Candidatus Berkiella aquae.

5 of 114

1.1

1.07

0.00015

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1307

Fatty acid biosynthesis, and Phosphopantetheine

9 of 13

2.3

6.98

1.93e-16

CL:1182

Carbon metabolism, and Fatty acid metabolic process

10 of 86

1.53

3.1

8.98e-13

CL:1311

Phosphopantetheine, and Fatty acid synthase activity

3 of 5

2.24

2.06

0.00011

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00061

Fatty acid biosynthesis

8 of 16

2.16

5.7

5.23e-14

map01212

Fatty acid metabolism

8 of 26

1.95

4.7

6.40e-13

map00620

Pyruvate metabolism

4 of 38

1.48

0.00019

map00640

Propanoate metabolism

3 of 23

1.58

1.27

0.0015

map00780

Biotin metabolism

3 of 26

1.52

1.21

0.0018

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009317

acetyl-CoA carboxylase complex

3 of 4

2.34

2.03

0.00014

GOCC:0005737

Cytoplasm

11 of 752

0.63

0.56

3.48e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0444

Lipid biosynthesis

9 of 24

2.04

5.59

4.52e-15

KW-0275

Fatty acid biosynthesis

7 of 12

2.23

5.35

1.67e-12

KW-0012

Acyltransferase

5 of 41

1.55

1.92

8.82e-06

KW-0963

Cytoplasm

6 of 226

0.89

0.71

0.0016

KW-0808

Transferase

7 of 407

0.7

0.52

0.0035

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01039

Carboxyl transferase domain

2 of 3

2.29

0.73

0.0453

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